Reliable Encoding of Stimulus Intensities Within Random Sequences of Intracellular Ca2+ Spikes
نویسندگان
چکیده
منابع مشابه
Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.
Ca(2+) is a ubiquitous intracellular messenger that regulates diverse cellular activities. Extracellular stimuli often evoke sequences of intracellular Ca(2+) spikes, and spike frequency may encode stimulus intensity. However, the timing of spikes within a cell is random because each interspike interval has a large stochastic component. In human embryonic kidney (HEK) 293 cells and rat primary ...
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Encoding and Decoding Spikes for Dynamic Stimuli
Naturally occurring sensory stimuli are dynamic. In this letter, we consider how spiking neural populations might transmit information about continuous dynamic stimulus variables. The combination of simple encoders and temporal stimulus correlations leads to a code in which information is not readily available to downstream neurons. Here, we explore a complex encoder that is paired with a simpl...
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ژورنال
عنوان ژورنال: Science Signaling
سال: 2014
ISSN: 1945-0877,1937-9145
DOI: 10.1126/scisignal.2005237